• Product NameCAY10603
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityCAY10603 is a potent and selective inhibitor of HDAC6 with IC50 of 2 pM, as compared with 271, 252, 0.42, 6851, and 90.7 nM for HDAC1, 2, 3, 8, and 10, respectively.
• Target NameHDAC inhibitor
• CAS No. 1045792-66-2
• Calculated MW 446.5
• Formulation C22H30N4O6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC(C)(C)OC(=O)NC1=CC=C(C=C1)C1=CC(=NO1)C(=O)NCCCCCCC(=O)NO
  Pathways:Chromatin/Epigenetic; DNA Damage/DNA Repair; NF-κb
  Receptor:HDAC1; HDAC6
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 5 mg/mL warmed (11.19 mM); DMSO: 89 mg/mL (199.32 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Kozikowski AP, et al. J Med Chem. 2008 Aug 14;51(15):4370-3.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting