• Product NameJ147
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityJ-147 is a broad spectrum neuroprotective phenyl hydrazide compound(EC50=60-115 nM) with significant neurotrophic properties related to the induction of brain-derived neurotrophic factor (BDNF).
• Target NameEpigenetic Reader Domain
• CAS No. 1146963-51-0
• Calculated MW 350.34
• Formulation C18H17F3N2O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC1=CC(=C(C=C1)N(C(=O)C(F)(F)F)/N=C/C2=CC(=CC=C2)OC)C
  Pathways:Chromatin/Epigenetic
  Receptor:BDNF
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Lapchak PA, et al. J Neurol Neurophysiol. 2013 Aug;4(3). pii: 158.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting