• Product NameJNJ-31020028
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityJNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22 rat); >100-fold selective versus human Y1/Y4/Y5 receptors.
• Target NameOthers antagonist
• CAS No. 1094873-14-9
• Calculated MW 565.68
• Formulation C34H36FN5O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CCN(CC)C(=O)C(N1CCN(CC1)C1=C(F)C=C(NC(=O)C2=CC=CC=C2C2=CN=CC=C2)C=C1)C1=CC=CC=C1
  Pathways:Others
  Receptor:Y2 receptor
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Shoblock JR, et al. Psychopharmacology (Berl). 2010 Feb;208(2):265-77.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting