• Product NameCHS 828
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityGMX1778(CHS-828) is a potent inhibitor of NAD+ biosynthesis enzyme NAMPT with IC50 <25 nM.
• Target NameNAMPT inhibitor
• CAS No. 200484-11-3
• Calculated MW 371.86
• Formulation C19H22ClN5O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:ClC1=CC=C(OCCCCCCN=C(NC#N)NC2=CC=NC=C2)C=C1
  Pathways:Metabolism
  Receptor:NAMPT; NAMPT
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Watson M, et al. Mol Cell Biol. 2009 Nov;29(21):5872-88.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting