• Product NameTP0903
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityTP-0903 is a potent and selective Axl kinase inhibitor with IC50 of 27 nM.
• Target NameTAM Receptor inhibitor
• CAS No. 1341200-45-0
• Calculated MW 516.06
• Formulation C24H30ClN7O2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CN(C)S(=O)(=O)C1=CC=CC=C1NC1=NC(NC2=CC=C(CN3CCN(C)CC3)C=C2)=NC=C1Cl
  Pathways:Tyrosine Kinase/Adaptors
  Receptor:AXL
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 6 mg/mL warmed (11.62 mM); DMSO: 7 mg/mL warmed (13.56 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Feneyrolles C, et al. Mol Y Ther. 2014 Sep;13(9):2141-8.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting