• Product NamePonalrestat
• Brief DescriptionInhibitors
• Purification99.75%
• Biological Activityponalrestat, an aldose reductase inhibitor, activates lipoprotein lipase (LPL) activity in the adipose tissue and alleviates the cachectic symptoms induced by B16 melanoma in mice
• Target NameReductase inhibitor
• CAS No. 72702-95-5
• Calculated MW 391.19
• Formulation C17H12BrFN2O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:OC(=O)CC1=NN(CC2=C(F)C=C(Br)C=C2)C(=O)C2=CC=CC=C12
  Pathways:Endocrinology/Hormones; Enzyme
  Receptor:Aldose reductase
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Pekiner C, McLean WG. Br J Pharmacol. 1990 Dec;101(4):978-80.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting