• Product NameU-104
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityU-104 is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki of 45.1 nM and 4.5 nM; low inhibition for CA I and CA II.
• Target NameCarbonic Anhydrase inhibitor
• CAS No. 178606-66-1
• Calculated MW 309.32
• Formulation C13H12FN3O3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:NS(=O)(=O)C1=CC=C(NC(=O)NC2=CC=C(F)C=C2)C=C1
  Pathways:Metabolism
  Receptor:Carbonic anhydrase I; Carbonic anhydrase II; Carbonic anhydrase IX; CAXII
  Boling pt:
  Melting pt:
  Solubility:DMSO: 62 mg/mL (200.43 mM)
  Appearance:WhitePowder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Lou Y, et al. Y Res. 2011 May 1;71(9):3364-76.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting