• Product NameA-803467
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityA-803467 is a selective NaV1.8 channel blocker with IC50 of 8 nM, blocks tetrodotoxin-resistant currents, exhibits >100-fold selectivity against human NaV1.2, NaV1.3, NaV1.5, and NaV1.7.
• Target NameSodium Channel inhibitor
• CAS No. 944261-79-4
• Calculated MW 357.79
• Formulation C19H16ClNO4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:COC1=CC(OC)=CC(NC(=O)C2=CC=C(O2)C2=CC=C(Cl)C=C2)=C1
  Pathways:Membrane transporter/Ion channel
  Receptor:Na(V1.8) channel
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 11 mg/mL (30.74 mM); DMSO: 72 mg/mL (201.23 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Jarvis MF, et al. Proc Natl Acad Sci U S A, 2007, 104(20), 8520-8525.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting