• Product NameNG-52
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityNG 52 (Compound 52 ) is a potent, cell-permeable, reversible, selective, and ATP-compatible inhibitor of the cell cycle-regulating kinase, Cdc28p (IC50 = 7 _mu_M), and the related Pho85p kinase (IC50 = 2 _mu_M).
• Target NameCDK inhibitor
• CAS No. 212779-48-1
• Calculated MW 346.81
• Formulation C16H19ClN6O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC(C)N1C=NC2=C1N=C(NCCO)N=C2NC1=CC(Cl)=CC=C1
  Pathways:Cell Cycle/Checkpoint
  Receptor:Cdc28p
  Boling pt:
  Melting pt:
  Solubility:DMSO: > 100mM
  Appearance:Off-white Color Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. ray NS, et al. Science. 1998 Jul 24;281(5376):533-8.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting