• Product NameTiplaxtinin(PAI-039)
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityTiplaxtinin(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.
• Target NamePAI-1 inhibitor
• CAS No. 393105-53-8
• Calculated MW 439.38
• Formulation C24H16F3NO4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:OC(=O)C(=O)C1=CN(CC2=CC=CC=C2)C2=C1C=C(C=C2)C1=CC=C(OC(F)(F)F)C=C1
  Pathways:Metabolism
  Receptor:PAI-1
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Elokdah H, et al. J Med Chem. 2004 Jul 1;47(14):3491-4.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting