• Product NameRG108
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityRG108 is an inhibitor of DNA methyltransferase with IC50 of 115 nM in a cell-free assay, does not cause trapping of covalent enzymes.
• Target NameDNA Methyltransferase inhibitor
• CAS No. 48208-26-0
• Calculated MW 334.33
• Formulation C19H14N2O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:C1=CC=C2C(=C1)C(=O)N(C2=O)[C@@H](CC3=CNC4=CC=CC=C43)C(=O)O
  Pathways:Chromatin/Epigenetic
  Receptor:DNA methyltransferase (DNMT)
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 67 mg/mL (200.4 mM); DMSO: 67 mg/mL (200.4 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Brueckner B, et al, Y Res, 2005, 65(14), 6305-6311.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting