• Product NameIDH1-IN-1
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityMutant IDH1-IN-1 is a potent mutant IDH1 R132H inhibitor with IC50 < 0.1 uM(A level in Patent); more bioactivity information in Patent WO2012009678A1(Example 135).
• Target NameDehydrogenase inhibitor
• CAS No. 1355326-21-4
• Calculated MW 498.59
• Formulation C30H31FN4O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC1=CC=CC=C1C(N(C(=O)CN1C=NC2=CC=CC=C12)C1=CC(F)=CC=C1)C(=O)NC1CCCCC1
  Pathways:Metabolism
  Receptor:mutant IDH1 R132H
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Crystalline Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Janeta Popovici-Muller, et al. Patent WO2012009678 A1.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting