• Product NameVarespladib (LY315920)
• Brief DescriptionInhibitors
• Purification99.70%
• Biological ActivityVarespladib (LY315920) is a potent and selective human non-pancreatic secretory phospholipase A2 (hnsPLA) inhibitor with IC50 of 7 nM. Phase 3.
• Target NamePhospholipase inhibitor
• CAS No. 172732-68-2
• Calculated MW 380.39
• Formulation C21H20N2O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:CCC1=C(C(=O)C(N)=O)C2=C(C=CC=C2OCC(O)=O)N1CC1=CC=CC=C1
  Pathways:Metabolism
  Receptor:hnsPLA2
  Boling pt:
  Melting pt:
  Solubility:DMSO: 76 mg/mL (199.79 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Draheim SE, et al. J Med Chem. 1996, 39(26), 5159-5175.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting