• Product NameFLT3-IN-1
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityFLT3-IN-1 is a novel potent and selective Flt3 inhibitor with IC50 of 10 nM; against FLT3-ITD-expressing MV4-11 cells with IC50 of 6 nM.
• Target NameFLT inhibitor
• CAS No. 1370256-78-2
• Calculated MW 537.66
• Formulation C25H27N7O3S2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CC1=CC=C(NC(=O)NC2=NN=C(SC3=NC=NC4=C3C=CC(OCCCN3CCOCC3)=C4)S2)C=C1
  Pathways:Angiogenesis; Tyrosine Kinase/Adaptors
  Receptor:FLT3
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:Faint Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Li WW, et al. J Med Chem. 2012 Apr 26;55(8):3852-66.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting