• Product NameWS3
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityWS3 is a β cell proliferation inducer via modulation of Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.
• Target NameEGFR inducer; IκB/IKK inhibitor
• CAS No. 1421227-52-2
• Calculated MW 569.58
• Formulation C28H30F3N7O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:CN1CCN(CC2=C(C=C(NC(=O)NC3=CC=C(OC4=NC=NC(NC(=O)C5CC5)=C4)C=C3)C=C2)C(F)(F)F)CC1
  Pathways:Angiogenesis; NF-κb; JAK/STAT signaling; Tyrosine Kinase/Adaptors
  Receptor:ErbB3-Binding Protein-1 (EBP1); IκB kinase
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 80 mg/mL warmed (140.45 mM); DMSO: 100 mg/mL warmed (175.56 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Shen W, et al. J Am Chem Soc. 2013, 135(5), 1669-1672.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting