• Product NameACT 058362; Palosuran
• Brief DescriptionInhibitors
• Purification98.04%
• Biological ActivityPalosuran (ACT-058362) is a new potent and specific antagonist of the human UT receptor with an IC50 of 3.6_plusmn_0.2 nM.
• Target NameGPR antagonist
• CAS No. 540769-28-6
• Calculated MW 418.53
• Formulation C25H30N4O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC1=NC2=CC=CC=C2C(NC(=O)NCCN2CCC(O)(CC3=CC=CC=C3)CC2)=C1
  Pathways:Endocrinology/Hormones
  Receptor:Urotensin Receptor (GPR14)
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Clozel M, et al. J Pharmacol Exp Ther. 2004 Oct;311(1):204-12.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting