• Product NamePurvalanol A
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityPurvalanol A is a potent, and cell-permeable CDK inhibitor with IC50 of 4 nM, 70 nM, 35 nM, and 850 nM for cdc2-cyclin B, cdk2-cyclin A, cdk2-cyclin E, and cdk4-cyclin D1, respectively.
• Target NameCDK inhibitor
• CAS No. 212844-53-6
• Calculated MW 388.89
• Formulation C19H25ClN6O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC(C)[C@H](CO)NC1=NC2=C(C(=N1)NC3=CC(=CC=C3)Cl)N=CN2C(C)C
  Pathways:Cell Cycle/Checkpoint
  Receptor:Cdc2/CyclinB; CDK2/CyclinA; CDK2/CyclinE; CDK4/CyclinD1
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 13 mg/mL warmed (33.42 mM); DMSO: 60 mg/mL warmed (154.28 mM)
  Appearance:Green Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Gray NS, et al. Science. 1998, 281(5376), 533-538.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting