• Product Namekb NB 142-70
• Brief DescriptionInhibitors
• Purification98.00%
• Biological Activitykb NB 142-70 is a selective protein kinase D (PKD) inhibitor (IC50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively).
• Target NameSerine/threonin kinase inhibitor
• CAS No. 1233533-04-4
• Calculated MW 251.32
• Formulation C11H9NO2S2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:OC1=CC2=C(SC3=C2SCCNC3=O)C=C1
  Pathways:Apoptosis
  Receptor:PKD1; PKD2; PKD3
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Young SH, et al. Am J Physiol Gastrointest Liver Physiol. 2012 Aug 1;303(3):G356-66.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting