• Product NamePimavanserin
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityPimavanserin(ACP-103) is a potent and selective 5-HT2A receptor inverse agonist with mean pIC50 of with 8.7 in the cell-based functional assay.
• Target Name5-HT Receptor agonist
• CAS No. 706779-91-1
• Calculated MW 427.55
• Formulation C25H34FN3O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:CC(C)COC1=CC=C(CNC(=O)N(CC2=CC=C(F)C=C2)C2CCN(C)CC2)C=C1
  Pathways:GPCR/G Protein; Neuroscience
  Receptor:5-HT2A
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Vanover KE, et al. J Pharmacol Exp Ther. 2006 May;317(2):910-8.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting