• Product NamePQ401
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityPQ401 inhibits autophosphorylation of IGF-1R domain with IC50 of <1 μM.
• Target NameIGF-1R inhibitor
• CAS No. 196868-63-0
• Calculated MW 341.79
• Formulation C18H16ClN3O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:COC1=C(NC(=O)NC2=CC(C)=NC3=CC=CC=C23)C=C(Cl)C=C1
  Pathways:Tyrosine Kinase/Adaptors
  Receptor:IGF-1R
  Boling pt:
  Melting pt:
  Solubility:DMSO: 32 mg/mL (93.62 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Gable KL, et al. Mol Y Ther, 2006, 5(4), 1079-1086.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting