• Product NameAPD 668
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityAPD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119 respectively.
• Target NameGPR agonist
• CAS No. 832714-46-2
• Calculated MW 477.51
• Formulation C21H24FN5O5S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC(C)OC(=O)N1CCC(CC1)OC1=NC=NC2=C1C=NN2C1=C(F)C=C(C=C1)S(C)(=O)=O
  Pathways:Endocrinology/Hormones
  Receptor:GPR119
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Semple G, et al. Bioorg Med Chem Lett. 2011 May 15;21(10):3134-41.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting