• Product NameBET bromodomain inhibitor
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityCPI-0610 is a potent, selective, and cell-active BET bromodomain inhibitor CPI-0610 inhibits BRD4-BD1 with IC50 of 39 nM in time-resolved fluorescence energy transfer (TR-FRET ) binding assay.
• Target Namec-Myc inhibitor; Epigenetic Reader Domain inhibitor
• CAS No. 1380087-89-7
• Calculated MW 365.81
• Formulation C20H16ClN3O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC1=NOC2=C1C1=CC=CC=C1C(=NC2CC(N)=O)C1=CC=C(Cl)C=C1
  Pathways:Cell Cycle/Checkpoint; Chromatin/Epigenetic
  Receptor:MYC; BRD4-BD1
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:Off-white Color Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Xiao Y, et al. Rheumatology (Oxford). 2015 Aug 31.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting