• Product NameA77-01
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityA 77-01 is a potent inhibitor of TGF-(beta) type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM.
• Target NameALK inhibitor
• CAS No. 607737-87-1
• Calculated MW 286.33
• Formulation C18H14N4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:CC1=CC=CC(=N1)C1=C(C=NN1)C1=CC=NC2=CC=CC=C12
  Pathways:Angiogenesis; Tyrosine Kinase/Adaptors
  Receptor:ALK5
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Tojo M, et al. Y Sci. 2005 Nov;96(11):791-800.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting