• Product NameSD-208
• Brief DescriptionInhibitors
• Purification98.72%
• Biological ActivitySD-208 is a selective TGF-βRI (ALK5) inhibitor with IC50 of 48 nM, >100-fold selectivity over TGF-βRII.
• Target NameTGF-beta/Smad inhibitor
• CAS No. 627536-09-8
• Calculated MW 352.75
• Formulation C17H10ClFN6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:FC1=C(C=C(Cl)C=C1)C1=NC2=NC=CN=C2C(NC2=CC=NC=C2)=N1
  Pathways:Stem Cells
  Receptor:TGF-βRI (ALK5)
  Boling pt:
  Melting pt:
  Solubility:DMSO: 9 mg/mL warmed (25.51 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Uhl M, et al. Y Res. 2004, 64(21), 7954-7961.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting