• Product NameYM155
• Brief DescriptionInhibitors
• Purification99.72%
• Biological ActivityYM155 (Sepantronium bromide) is a novel small molecule survivin suppressant with an IC50 of 0.54 nM for the inhibition of survivin promoter activity.
• Target NameSurvivin inhibitor
• CAS No. 781661-94-7
• Calculated MW 443.26
• Formulation C20H19BrN4O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:[Br-].COCCN1C(C)=[N+](CC2=NC=CN=C2)C2=C1C(=O)C1=CC=CC=C1C2=O
  Pathways:Apoptosis
  Receptor:Survivin
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 6 mg/mL (13.53 mM); Water: 89 mg/mL (200.77 mM); DMSO: 55 mg/mL (124.07 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Iwasa, et al. Clinical Y Research (2008), 14(20), 6496-6504

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting