• Product NameIbudilast
• Brief DescriptionInhibitors
• Purification99.90%
• Biological ActivityIbudilast(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor which has been marketed for treating asthma.
• Target NamePDE inhibitor
• CAS No. 50847-11-5
• Calculated MW 230.51
• Formulation C14H18N2O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Respiratory system
  SMILES:CC(C)C(=O)C1=C2C=CC=CN2N=C1C(C)C
  Pathways:Metabolism
  Receptor:PDE
  Boling pt:
  Melting pt:
  Solubility:DMSO: 28 mg/mL;100 mM in Ethanol
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Yamazaki T, et al. Eur J Pharmacol. 2010 Oct 29.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting