• Product Name1NM-PP1
• Brief DescriptionInhibitors
• Purification98.00%
• Biological Activity1NM-PP1(PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors(IC50=28 uM vSrc; 4.2 nM v-Src-as1 I338G).
• Target NameCDK inhibitor
• CAS No. 221244-14-0
• Calculated MW 331.41
• Formulation C20H21N5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CC(C)(C)N1N=C(CC2=CC3=CC=CC=C3C=C2)C2=C1N=CN=C2N
  Pathways:Cell Cycle/Checkpoint
  Receptor:CDK7
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Papa FR, et al. Science. 2003 Nov 28;302(5650):1533-7.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting