• Product NameMG-132
• Brief DescriptionInhibitors
• Purification95.00%
• Biological ActivityMG-132 is an inhibitor of proteasome with IC50 of 100 nM, and also inhibits calpain with IC50 of 1.2 _mu_M.
• Target NameProteasome inhibitor
• CAS No. 133407-82-6
• Calculated MW 475.62
• Formulation C26H41N3O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC(C)C[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCC1=CC=CC=C1
  Pathways:Proteases/Proteasome; Ubiquitination
  Receptor:Proteasome
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 95 mg/mL (199.73 mM); DMSO: 95 mg/mL (199.73 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Tsubuki S, et al. J Biochem, 1996, 119(3), 572-576.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting