• Product NameSuramin Sodium Salt
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivitySuramin sodium salt is a polysulfonated naphthylurea that inhibits the binding of calmodulin to recognition sites on the ryanodine receptor-1 (IC50 = 4.9 μM), blocks G protein coupling to GPCRs, and non-selectively antagonizes P2 purinergic receptors (10-100 μM).
• Target NameTopoisomerase inhibitor
• CAS No. 129-46-4
• Calculated MW 1429.15
• Formulation C51H34N6Na6O23S6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:O=C(C1=CC=C(C)C(NC(C2=CC(NC(NC3=CC(C(NC4=C(C)C=CC(C(NC5=C(C(S(=O)([O-])=O)=CC(S(=O)([O-])=O)=C6)C6=C(S(=O)([O-])=O)C=C5)=O)=C4)=O)=CC=C3)=O)=CC=C2)=O)=C1)NC7=CC=C(S(=O)([O-])=O)C8=C7C(S(=O)([O-])=O)=CC(S(=O)([O-])=O)=C8.[Na+].[Na+].[Na+].[Na+].[Na+].
  Pathways:DNA Damage/DNA Repair
  Receptor:Topo II
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Klinger M, et al. Biochem J. 2001 May 1;355(Pt 3):827-33.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting