• Product NameTWS119
• Brief DescriptionInhibitors
• Purification98.14%
• Biological ActivityTWS119 is a GSK-3β inhibitor with IC50 of 30 nM in a cell-free assay; capable of inducing neuronal differentiation and may be useful to stem cell biology.
• Target NameGSK-3 inhibitor
• CAS No. 601514-19-6
• Calculated MW 318.33
• Formulation C18H14N4O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:C1=CC(=CC(=C1)N)C2=CC3=C(N2)N=CN=C3OC4=CC=CC(=C4)O
  Pathways:PI3K/Akt/mTOR signaling; Stem Cells
  Receptor:GSK-3β
  Boling pt:
  Melting pt:
  Solubility:DMSO: 64 mg/mL (201.04 mM)
  Appearance:Gray Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Ding S, et al, Pro Natl Acad Sci U S A, 2003, 100(13), 7632-7637.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting