• Product Name2-NP
• Brief DescriptionInhibitors
• Purification98.00%
• Biological Activity2-NP increased the duration of STAT1 tyrosine phosphorylation in response to IFN-gamma, and this may underlie its enhancement of STAT1-dependent transcription. Reflecting the fact that STAT1 can exert tumor-suppressive effects, 2-NP enhanced the ability of IFN-gamma to inhibit the proliferation of human breast Y and fibrosarcoma cells.
• Target NameSTAT activator
• CAS No. 65182-56-1
• Calculated MW 222.24
• Formulation C14H10N2O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:C1=C/C(=C/2\C=CC3=C(N2)N=CC=C3)/C(=O)C=C1
  Pathways:JAK/STAT signaling; Stem Cells
  Receptor:STAT1
  Boling pt:
  Melting pt:
  Solubility:DMSO: > 10 mM
  Appearance:Orange Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Lynch RA, et al. Y Res. 2007 Feb 1;67(3):1254-61.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting