• Product NameZebularine
• Brief DescriptionInhibitors
• Purification99.04%
• Biological ActivityZebularine is a DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases, also inhibits cytidinedeaminase with Ki of 2 μM in a cell-free assay.
• Target NameDNA Methyltransferase inhibitor
• CAS No. 3690-10-6
• Calculated MW 228.2
• Formulation C9H12N2O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:C1=CN(C(=O)N=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
  Pathways:Chromatin/Epigenetic
  Receptor:Cytidine deaminase
  Boling pt:
  Melting pt:
  Solubility:Water: 46 mg/mL (201.57 mM); DMSO: 46 mg/mL (201.57 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Zhou L, et al. J Mol Biol, 2002, 321(4), 591-599.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting