• Product NameSQ 22536
• Brief DescriptionInhibitors
• Purification98.80%
• Biological ActivityThe adenosine analogue 9-(Tetrahydro-2-furyl)adenine, SQ 22536, inhibited adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] activity of crude membrane preparations from catfish (Ictalurus melas) and rat isolated hepatocytes in a non-competitive manner. The IC50s were reduced in the presence of NaF.
• Target NameAChR inhibitor
• CAS No. 17318-31-9
• Calculated MW 205.22
• Formulation C9H11N5O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C1CC(OC1)N2C=NC3=C2N=CN=C3N
  Pathways:Neuroscience
  Receptor:adenylate cyclase
  Boling pt:
  Melting pt:
  Solubility:DMSO > 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Fabbri E, et al. J Enzyme Inhib. 1991;5(2):87-98.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting