• Product NameSodium orthovanadate
• Brief DescriptionInhibitors
• Purification96.00%
• Biological ActivitySodium orthovanadate is a commonly used general inhibitor for PTP (protein tyrosine phosphatases), alkaline phosphatase (ALP) and ATPase. Na3VO4 acts as a competitive inhibitor and is completely reversible upon the addition of EDTA or by dilution. The PTP activities are conveniently separable from the protein phosphoseryl and phosphothreonyl phosphatase (PSP) activities inhibited by Fluoride and EDTA. Vanadate is routinely used to preserve the protein tyrosyl phosphorylation state in cells, cell lysates, and protein tyrosine kinase assays. Sodium Orthovanadate is an inhibitor of AK and PFK.
• Target NameATPase inhibitor; Phosphatase inhibitor
• CAS No. 13721-39-6
• Calculated MW 183.9
• Formulation Na3O4V
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:[Na+].O=[V-3](=O)(=O)=O
  Pathways:Membrane transporter/Ion channel; Others
  Receptor:(Na,K)-ATPase; Phosphatase
  Boling pt:
  Melting pt:850-866C
  Solubility:Water: 37 mg/mL (201.18 mM)
  Appearance:White Crystal
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Wu Y, et al. Acta Pharmacol Sin, 2005, 26(3), 345-352. 2. Cantley LC Jr, et al. J Biol Chem, 1977, 252(21), 7421-7423.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting