• Product Name6-Mercaptopurine monohydrate
• Brief DescriptionInhibitors
• Purification99.92%
• Biological Activityercaptopurine is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.
• Target NameDNA/RNA Synthesis inhibitor; Others inhibitor
• CAS No. 6112-76-1
• Calculated MW 170.19
• Formulation C5H6N4OS
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:O.S=C1N=CNC2=C1NC=N2
  Pathways:DNA Damage/DNA Repair; Others
  Receptor:DNA synthesis; PRPP Amidotransferase
  Boling pt:490.6C
  Melting pt:>300C
  Solubility:DMSO: 100 mg/mL; Water <1 mg/mL
  Appearance:Faint Yellow Crystal Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Sahasranaman S, et al. Eur J Clin Pharmacol, 2008, 64(8), 753-767.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting