• Product NameTheophylline-7-acetic acid
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityTheophylline-7-acetic acid is a stimulant drug of the xanthine chemical class. It acts as an adenosine receptor antagonist. It is combined with diphenhydramine in the pharmaceutical preparation etanautine to help offset its stimulant effects
• Target NameAdenosine Receptor antagonist; HDAC inhibitor; PDE inhibitor; PKA activator; TNF inhibitor
• CAS No. 652-37-9
• Calculated MW 238.2
• Formulation C9H10N4O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:CN1C2=C(N(CC(O)=O)C=N2)C(=O)N(C)C1=O
  Pathways:Chromatin/Epigenetic; Apoptosis; GPCR/G Protein; Metabolism; DNA Damage/DNA Repair; NF-κb
  Receptor:A1; A2; A3; HDAC2; PDE4; PKA; TNF-α
  Boling pt:
  Melting pt:270-272C
  Solubility:Soluble in Water
  Appearance:White Crystal Solid
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Voynikov Y, et al. Bioorg Med Chem Lett. 2014 Jul 15; 24(14):3043-5.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting