• Product NameSC-202671
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityTCS JNK 5a(JNK Inhibitor IX) is a selective inhibitor of JNK2 and JNK3 (pIC50 values are 6.7, 6.5, <5.0 and <4.8 for JNK3, JNK2, JNK1 and p38α respectively); displays no significant activity at a range of other protein kinases including EGFR, ErbB2, cdk2, PLK-1 and Src (pIC50 < 5.0).
• Target NameJNK inhibitor
• CAS No. 312917-14-9
• Calculated MW 332.42
• Formulation C20H16N2OS
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:O=C(NC1=C(C#N)C2=C(CCCC2)S1)C1=CC=CC2=CC=CC=C12
  Pathways:MAPK
  Receptor:JNK2; JNK3
  Boling pt:486.8C
  Melting pt:
  Solubility:DMSO: 20 mg/mL (60.16 mM)
  Appearance:Faint Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Angell RM, et al. Bioorg Med Chem Lett. 2007, 17(5), 1296-1301.2. Rudolf E, et al. Toxicol Lett. 2009, 188(3), 236-242.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting