• Product NameCariporide
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityCariporide (HOE-642), a potent NHE1 inhibitor, has inhibitory effects on the degranulation of human platelets, the formation of platelet-leukocyte-aggregates, and the activation of the GPIIb/IIIa receptor (PAC-1).
• Target NameOthers inhibitor
• CAS No. 159138-80-4
• Calculated MW 283.35
• Formulation C12H17N3O3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:CC(C)C1=C(C=C(C=C1)C(=O)N=C(N)N)S(C)(=O)=O
  Pathways:Others
  Receptor:NHE2
  Boling pt:542.8C
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Yang X, et al. J Surg Res. 2013 Dec;185(2):797-804. 2. Wu S, et al. Pharmacology. 2013; 91(3-4):123-30.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting