• Product NameWnt-C59
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityWnt-C59(C59) is a very potent and highly selective Wnt signaling antagonist with an IC50 ~ 74 pM in the Wnt signaling reporter assay.
• Target NamePorcupine inhibitor
• CAS No. 1243243-89-1
• Calculated MW 379.45
• Formulation C25H21N3O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC1=NC=CC(=C1)C1=CC=C(CC(=O)NC2=CC=C(C=C2)C2=CN=CC=C2)C=C1
  Pathways:Stem Cells
  Receptor:Porcn
  Boling pt:
  Melting pt:
  Solubility:DMSO: 76 mg/mL (200.28 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Proffitt KD, et al. Y Res. 2013 Jan 15;73(2):502-7.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting