• Product NameDY-131
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityDY131(GSK 9089) is a novel selective agonist of ERR_beta_ and ERR_gamma_; displays minimal activity at ERR_alpha_, ER_alpha_ and ER_beta_ at concentrations up to 30 _mu_M.
• Target NameEstrogen/progestogen Receptor agonist
• CAS No. 95167-41-2
• Calculated MW 311.38
• Formulation C18H21N3O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Endocrine system
  SMILES:CCN(CC)C1=CC=C(C=C1)/C=N/NC(=O)C2=CC=C(C=C2)O
  Pathways:Endocrinology/Hormones
  Receptor:ERRβ; ERRγ
  Boling pt:
  Melting pt:
  Solubility:DMSO: 14 mg/mL
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Wang Y, et al. ACS Chem Biol. 2012,15;7(6):1040-8.2. Kumar P, et al. Mol Endocrinol. 2011;25(9): 1513-26.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting