• Product NameUNC669
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityUNC669 is a potent and selective MBT (malignant brain tumor) inhibitor with IC50 of 6 μM for L3MBTL1, 5- and 11-fold selective over L3MBTL3 and L3MBTL4.
• Target NameEpigenetic Reader Domain antagonist
• CAS No. 1314241-44-5
• Calculated MW 338.24
• Formulation C15H20BrN3O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:BrC1=CN=CC(=C1)C(=O)N1CCC(CC1)N1CCCC1
  Pathways:Chromatin/Epigenetic
  Receptor:L3MBTL1; L3MBTL3; L3MBTL4
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 68 mg/mL (201.04 mM); DMSO: 11 mg/mL (32.52 mM)
  Appearance:Faint Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Herold JM, et al. J Med Chem. 2011, 54(7), 2504-2511.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting