• Product NameA-205804
• Brief DescriptionInhibitors
• Purification98.52%
• Biological ActivityA-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively.
• Target NameIntegrin inhibitor
• CAS No. 251992-66-2
• Calculated MW 300.41
• Formulation C15H12N2OS2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC1=CC=C(SC2=C3C=C(SC3=CN=C2)C(N)=O)C=C1
  Pathways:Cytoskeletal Signaling
  Receptor:E-selectin; ICAM-1
  Boling pt:581.35C
  Melting pt:
  Solubility:DMSO: 60 mg/mL (199.73 mM)
  Appearance:White Crystalline Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Zhu GD, et al. J Med Chem, 2001, 44(21), 3469-3487.2. Stewart AO, J Med Chem, 2001, 44(6), 988-1002.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting