• Product NameVER-50589
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityVER-50589 is a potent HSP90 inhibitor with IC50 of 21 nM for HSP90β.
• Target NameHSP inhibitor
• CAS No. 747413-08-7
• Calculated MW 388.8
• Formulation C19H17ClN2O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CCNC(=O)C1=C(/C(=C/2\C=C(C(=CC2=O)O)Cl)/ON1)C3=CC=C(C=C3)OC
  Pathways:Cytoskeletal Signaling; Metabolism
  Receptor:HSP90β
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 77 mg/mL (198.04 mM); DMSO: 77 mg/mL (198.04 mM)
  Appearance:White Crystalline Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Sharp SY, et al. Mol Y Ther. 2007, 6(4), 1198-1211.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting