• Product NameAM281
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityCannabinoid antagonist AM 281 reduces mortality rate and neurologic dysfunction after cecal ligation and puncture in rats.
• Target NameCannabinoid Receptor antagonist
• CAS No. 202463-68-1
• Calculated MW 557.21
• Formulation C21H19Cl2IN4O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:ClC1=CC(Cl)=CC=C1N2C(C3=CC=C(I)C=C3)=C(C)C(C(NN4CCOCC4)=O)=N2
  Pathways:GPCR/G Protein
  Receptor:CB
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Kadoi Y, et al. Crit Care Med. 2005 Nov;33(11):2629-36.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting