• Product NameCAY10683 (SantacruzaMate A)
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivitySantacruzamate A (CAY10683) is a potent and selective HDAC inhibitor with IC50 of 119 pM for HDAC2, >3600-fold selectivity over other HDACs.
• Target NameHDAC inhibitor
• CAS No. 1477949-42-0
• Calculated MW 278.35
• Formulation C15H22N2O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CCOC(=O)NCCCC(=O)NCCC1=CC=CC=C1
  Pathways:Chromatin/Epigenetic; DNA Damage/DNA Repair; NF-κb
  Receptor:HDAC2; HDAC4; HDAC6
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 55 mg/mL (197.59 mM); DMSO: 55 mg/mL (197.59 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Pavlik CM, et al. J Nat Prod. 2013, 76(11), 2026-2033.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting