• Product NameBQU57
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityBQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth similar to depletion of Ral by siRNA. The IC50 for BQU57 of 2.0 _mu_M in H2122 and 1.3 _mu_M in H358.
• Target NameOthers inhibitor
• CAS No. 1637739-82-2
• Calculated MW 334.3
• Formulation C16H13F3N4O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CN1N=C(C)C2=C1OC(N)=C(C#N)C2C1=CC=C(C=C1)C(F)(F)F
  Pathways:Others
  Receptor:Ral
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 20 mg/mL warmed (59.86 mM); DMSO: 66 mg/mL warmed (197.54 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Yan C, et al. Nature. 2014 Nov 20; 515(7527): 443-447.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting