• Product NameBPR1J-097
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityBPR1J-097 is a novel small molecule FLT-3 inhibitor(IC50=117 nM) with promising in vivo anti-tumour activities; inhibits FLT-3 D835Y with an IC50 of 3 nM.
• Target NameFLT inhibitor
• CAS No. 1327167-19-0
• Calculated MW 516.62
• Formulation C27H28N6O3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CN1CCN(CC1)C1=CC=C(C=C1)C(=O)NC1=NNC(=C1)C1=CC(NS(=O)(=O)C2=CC=CC=C2)=CC=C1
  Pathways:Angiogenesis; Tyrosine Kinase/Adaptors
  Receptor:FLT3
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:Faint Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Lin WH, et al. Br J Y. 2012 Jan 31;106(3):475-81.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting