• Product NameITD-1
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityITD-1 is an inducer of TGF_beta_ type II receptor degradation-1, is a potent and highly selective TGF_beta_ pathway inhibitor (IC50 = 0.85 uM).
• Target NameTGF-beta/Smad inhibitor
• CAS No. 1099644-42-4
• Calculated MW 415.52
• Formulation C27H29NO3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:CCOC(=O)C1=C(C)NC2=C(C1C1=CC=C(C=C1)C1=CC=CC=C1)C(=O)CC(C)(C)C2
  Pathways:Stem Cells
  Receptor:TGFβ
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Crystalline Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Willems E, et al. Cell Stem Cell. 2012 Aug 3;11(2):242-252.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting