• Product NameBG45
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityBG45 is a class I HDAC inhibitor with IC50 of 289 nM, 2.0 ?M, 2.2 ?M and >20 ?M for HDAC3, HDAC1, HDAC2, and HDAC6 in cell-free assays, respectively.
• Target NameHDAC inhibitor
• CAS No. 926259-99-6
• Calculated MW 214.22
• Formulation C11H10N4O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:NC1=CC=CC=C1NC(=O)C1=NC=CN=C1
  Pathways:Chromatin/Epigenetic; DNA Damage/DNA Repair; NF-κb
  Receptor:HDAC1; HDAC2; HDAC3; HDAC6
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 2 mg/mL warmed (9.33 mM); DMSO: 42 mg/mL (196.06 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Minami J, et al. Leukemia. 2014, 28(3), 680-689.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting