• Product NameTrelagliptin succinate
• Brief DescriptionInhibitors
• Purification99.27%
• Biological ActivityTrelagliptin(SYR-472) is a long acting dipeptidyl peptidase-4 (DPP-4) inhibitor that is being developed for the treatment of type 2 diabetes (T2D).
• Target NameDPP-4 inhibitor
• CAS No. 1029877-94-8
• Calculated MW 475.47
• Formulation C22H26FN5O6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:CN1C(=O)C=C(N(C1=O)CC2=C(C=CC(=C2)F)C#N)N3CCC[C@H](C3)N.C(CC(=O)O)C(=O)O
  Pathways:Proteases/Proteasome
  Receptor:DPP-4
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. McKeage K. Drugs. 2015 Jul;75(10):1161-4.2. Inagaki N, et al. Lancet Diabetes Endocrinol. 2015 Mar;3(3):191-7.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting